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Descriptor English: Receptors, GABA-B
Descriptor Spanish: Receptores de GABA-B
Descriptor receptores de GABA-B
Entry term(s) receptores GABA-B
receptores de baclofeno
Scope note: Proteínas de la superficie celular que se unen al GABA y que influyen sobre las células por medio de interacciones con las proteínas G. Los receptores de GABA-B se caracterizan farmacológicamente por su insensibilidad al bloqueador bicuculina y su sensibilidad al agonista L-baclofeno. Se encuentran tanto pre como postsinápticamente, y actúan de forma diversa por inhibición de la adenilato ciclasa, activación de la fosfolipasa A2, activación de los canales de potasio, e inactivación de los canales de calcio activados por el voltaje.
Descriptor Portuguese: Receptores de GABA-B
Descriptor French: Récepteurs GABA-B
Entry term(s): Baclofen Receptor
Baclofen Receptors
GABA B Receptor
GABA B Receptors
GABA-B Receptor
GABA-B Receptors
Receptor, Baclofen
Receptor, GABA-B
Receptors, Baclofen
Receptors, GABA B
Tree number(s): D12.776.543.750.695.300
D12.776.543.750.720.200.300.320
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018080
Scope note: A subset of GABA RECEPTORS that signal through their interaction with HETEROTRIMERIC G-PROTEINS.
Allowable Qualifiers: AD administration & dosage
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Entry Combination: antagonists & inhibitors:GABA-B Receptor Antagonists
agonists:GABA-B Receptor Agonists
Previous Indexing: GABA (1980-1993)
Receptors, Cell Surface (1981-1984)
Receptors, GABA-A (1985-1993)
Public MeSH Note: 94; BACLOFEN RECEPTOR was indexed under RECEPTORS, GABA-BENZODIAZEPINE 1985-93
Online Note: use RECEPTORS, GABA-B (NM) to search BACLOFEN RECEPTORS 1985-93
History Note: 94; BACLOFEN RECEPTORS was BACLOFEN RECEPTOR (NM) 1985-93
Entry Version: RECEPT GABA B
DeCS ID: 31126
Unique ID: D018080
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1993/06/21
Revision Date: 2016/06/17
Receptors, GABA-B - Preferred
Concept UI M0027274
Scope note A subset of GABA RECEPTORS that signal through their interaction with HETEROTRIMERIC G-PROTEINS.
Preferred term Receptors, GABA-B
Entry term(s) Baclofen Receptor
Baclofen Receptors
GABA B Receptor
GABA B Receptors
GABA-B Receptor
GABA-B Receptors
Receptor, Baclofen
Receptor, GABA-B
Receptors, Baclofen
Receptors, GABA B



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